A High Fat Diet Can Lead To Overeating, Says New Research

There's One Major Downside To The Keto Diet That No One Is Talking About

And it's going to be problematic if you're looking to lose weight - by Lucy Bode

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It’s had athletes such as Lebron James and Tim Tebow singing its praises. But if this new study is anything to go by, there’s one major reason to give the high-fat, low-carb keto diet a miss.

The research – published in the journal Science Translational Medicine – found that when mice were fed a high-fat diet, they were more likely to overeat. This is because they started producing a hormone called MMP-2, which essentially blocks leptin from binding to its receptors (FYI: leptins job is to inform the brain that your stomach is full.)

The researchers believe these findings explain why leptin resistance is so common among patients with obesity. In fact, they hope that in the future clinicians will be able to treat this condition by blocking the MMP-2.

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That said, the study has its limitations: the type of fat the mice were fed wasn’t disclosed (i.e, whether it was monounsaturated fats like avo, nuts and olive oil or unhealthy saturated or trans fats.) Of course, more research on humans is needed too:

“We opened a new field of study for metabolic disease,” said Rafi Mazor, a research scientist at the University of California San Diego and the study’s lead author.

“We need to ask what other pathways, in addition to leptin and its receptors, undergo a similar destructive process and what the consequences might be.”

This article originally appeared on Women's Health.

Lucy Bode

Lucy is WH’s Digital Editor, Features Writer, social media guru and resident woo. A long black lover and foodie at heart, she considers peanut butter an hourly staple and believes chardonnay is the superior drop. When she's not at the beach, barre or yoga studio you'll find her coming up with new and improved ways to kill her unkillable houseplants

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