The 2day FM radio and television star posted a photo to his social media account with his nose covered in bandages after seeking treatment.
"Guys I have a secret to tell you: there are several band aids on my nose," Blake captions the photo.
"You would never know this if I didn't tell you because they are skin coloured and therefore, according to the medical industry, perfectly camouflaged. But I feel it's better to be honest. I don't just have a beautiful, natural, large, handsome, very rough textured nose. (PS get skin checks)"
His fans rallied, offering their support for the Aussie comedian: "Agree @hamishblakeshots I just had surgery on Friday to remove a level 3 melanoma, Skin checks save lives!" Writes one of his followers.
Previously Hugh Jackman went public with his skin cancer battles, having five skin cancers removed.
It's important to regularly get checked, especially with high exposure to the sun during the Summer months. Australia has one of the highest rates of skin cancer in the world.