A case study published in an issue of Urology Case Reports detailed the experience of a 25-year-old man who suffered from the uncommon condition since puberty. He reported dreading ejaculation and minimised sexual activity, including masturbation, to avoid the symptoms, which could occur immediately after orgasm or two or three days later. They'd often last up to two weeks.
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After seeing several medical experts, doing extensive online research, and trying a range of diets and supplements, he was found to have testosterone deficiency and was successfully treated with hormone therapy.
The study says the prevalence of POIS is unknown and difficult to determine, as sufferers are unlikely to seek medical attention and most physicians are unaware of the syndrome.
Although treatment worked for the case study, there's still no known cure for POIS and medical experts still don’t fully understand why it occurs.